Exosome Therapy for Hair Loss
What are exosomes?
Exosomes are extracellular vesicles that are produced by mesenchymal stem cells which are involved in cell communication. Other cells react to the messaging signals from the exosomes and will change their behavior accordingly. Scientists are now able to isolate and deliver these beneficial signalers directly rather than the stem cells themselves.
Exosomes are isolated from donated human amniotic mesenchymal stem cells and purified using proprietary processing. The unique benefit of these exosomes is that they are stem cell-derived and bring a wide array of growth factors. Because they’re so small and nimble, exosomes can remain hidden in the bloodstream, and carry multiple doses of proteins across barriers that cells are not able to cross.
What is exosome therapy for hair loss?
By injecting exosomes and growth factors, it has been clinically shown to help regenerate and regrow hair as a treatment for hair loss in both men and women in the earlier stages of hair loss.
How long does it take to see results from exosome therapy for hair loss?
Exosome therapy may begin promoting natural hair growth in as little as two to three months. New hair growth can continue over the course of a year, with the most noticeable results usually being seen six months after treatment has been administered.
How long do I have to wait before another session of exosome therapy for hair loss?
We typically recommend waiting 6 to 8 months after the last treatment to re-evaluate and before potentially performing another treatment of exosome injections if it is necessary.
How are the exosomes processed, and are they safe to use?
Vinings Surgery Center uses exosomes which are procured and processed in the United States according to standards and regulations established by the American Association of Tissue Banks (AATB), and the United States Food & Drug Administration (FDA). All local donors.
Donor ethics and non-reactive FDA approved serological screening includes:
- Donor consent prior to collections
- HBsAG (Hepatitis B Surface Antigen)
- HBcAb (Hepatitis B core Antibody)
- HCV (Hepatitis C Antibody)
- HIV 1/11-Ab (HIV Nucleic Acid Test)
- HCV NAt (HCV Nucleic Acid Test)
Are exosomes tested for HIV, Hepatitis and other infectious diseases?
Yes. Exosomes are tested for variety of diseases, including HIV, hepatitis, and others. Each package comes with the tests performed. At the time of procedure, Dr. Colgrove opens the package and shows the patient the sheet of all the passed tests.
How many exosomes are in each vial?
For hair loss, we utilize 400 plus billion exosomes per vial. We have found that a 400 billion exosomes product is more than sufficient to regenerate hair growth.
How are exosome treatments different from PRP (Platelet Rich Plasma) treatments?
PRP stands for platelet rich plasma. It begins with centrifuging a patient’s blood so we can concentrate the growth factors and platelets naturally present. PRP however does not provide any stem cells or exosomes because as we age our bodies contain less and less stem cells in our blood.
A normal PRP treatment does not include any stem cells. PRP involves concentrating only growth factors and platelets to be injected into the patient. Often, patients and sometimes doctors confuse PRP with concentrated stem cells but blood is not the optimal source to obtain stem cells. Originally stem cells would come from fat collected during liposuction. But that process is very labor intensive and not worth the effort especially when considering that stem cells are not as potent as the source patient has aged. Vining Surgery Center uses exosomes which are sourced from amniotic mesenchymal stem cells.
How long do the last in your body?
Exosomes are present 6 to 8 months after the final treatment.
Can the patient take NSAIDS?
No. It is ideal for the patient to stop taking NSAIDS for about 3 days prior to the injection and for 3 weeks after. A part of the exosomes function is a prostaglandin response which would be inhibited by the NSAIDS. Please note, NSAIDS will NOT destroy the injected cells, just potentially lessen the effects. It is also known that not taking NSAIDS is purely to optimize the final results.
Are there any contraindications for exosome injections?
There are no contraindications for exosome injections.
What preparation do I need for the day of the procedure?
Patients are advised to:
- Drink a lot of fluid one day prior to the procedure
- Have breakfast the morning of their procedure
- Avoid Aspirin, Naproxen, Ibuprofen and other NSAIDs 3 days prior to the procedure and 3 weeks after the procedure.
Are there any restrictions after the procedure?
There are really not many restrictions. Most patients return to work or their routine that day. You can exercise and do your normal activities. It is advised to avoid aspirin, Naproxen, Ibuprofen and other NSAIDs for 3 weeks following the procedure.
Can I combine exosome therapy with other hair loss modalities?
Yes. We recommend patients use Propecia, Finasteride or Minoxidil in conjunction with exosome treatments for hair loss.
Do exosomes cause cancer or cause cancer to grow?
Currently there no large direct studies that can show exosomes or stem cells do not cause cancer, but there are studies where stem cells have been utilized to treat cancer, and the conclusion from these studies is that since the stem cells work to suppress cancer cells, it is assumed that they will neither help proliferate cancer cells nor cause the formation of cancer cells in the first place.
Can exosomes be used for Alopecia Areata?
Yes. Clinical and anecdotal results have shown tremendous efficacy for when exosome therapy is utilized.